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Reproducibility of Tumor Segmentation Outcomes with a Deep Learning Model

2023· article· en· W4360981867 on OpenAlexaff
Morgane Des Ligneris, Axel Bonnet, Yohan Chatelain, Tristan Glatard, Michaël Sdika, Gaël Vila, Valentine Wargnier-Dauchelle, Sorina Camarasu-Pop, Carole Frindel

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsConcordia University
FundersLabEx PRIMESAgence Nationale de la Recherche
KeywordsReproducibilitySegmentationPipeline (software)Computer scienceBenchmark (surveying)Stability (learning theory)DiceDeep learningArtificial intelligenceHausdorff distanceRange (aeronautics)Image segmentationPattern recognition (psychology)Machine learningStatisticsMathematicsCartographyEngineeringGeography

Abstract

fetched live from OpenAlex

In the last few years, there has been a growing awareness of reproducibility concerns in many areas of science. In this work, our goal is to evaluate the reproducibility of tumor segmentation outcomes produced with a deep segmentation model when MRI images are pre-processed (i) with two different versions of the same pre-processing pipeline, and (ii) by introducing numerical perturbations that mimic executions on different environments. Results show that these two variability sources can lead to important variations of segmentation outcomes: Dice can go as low as 0.59 and Hausdorff distance as high as 84.75. Moreover, both cases show a similar range of values, suggesting that the underlying causes for instability may be numerical stability. This work can be used as a benchmark to improve the numerical stability of the pipeline.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.991
Threshold uncertainty score0.048

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.042
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.320
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designObservational
DomainReproducibility
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2023
Admission routes1
Has abstractyes

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