Characterization of highly pathogenic clade 2.3.4.4b H5N1 mink influenza viruses
Bibliographic record
Abstract
Highly pathogenic avian H5 influenza viruses (HPAI) have caused more than 957 human infections, but do not transmit via respiratory droplets among mammals, although genetically modified HPAI H5 viruses can acquire this ability.1,2 HPAI H5N1 viruses of clade 2.3.4.4b emerged in Europe in late 2020 and have caused major outbreaks in multiple continents. Mass mortality events of 2.3.4.4b clade viruses in mink3 and sea mammals4 suggest high infectivity and pathogenicity among mammals. A recent study evaluated the pathogenicity and transmissibility of several clade 2.3.4.4b H5N1 viruses isolated in Canada.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".