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Record W4391053849 · doi:10.1136/bmjopen-2023-074191

Access to cancer clinical trials for racialised older adults: an equity-focused rapid scoping review protocol

2024· article· en· W4391053849 on OpenAlexaff
Vivian Li, Shabbir M.H. Alibhai, Kenneth Noel, Rouhi Fazelzad, Kristen R. Haase, Caroline Mariano, Sara Durbano, Schroder Sattar, Lorelei Newton, David E. Dawe, Jennifer Bell, Tina Hsu, Sabrina T. Wong, Aïsha Lofters, Jacqueline L. Bender, Jackie Manthorne, Martine Puts

Bibliographic record

VenueBMJ Open · 2024
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsCanadian Breast Cancer NetworkCanadian Cancer SocietyWomen's College HospitalOttawa Regional Cancer FoundationUniversity Health NetworkOttawa HospitalCancerCare ManitobaUniversity of VictoriaUniversity of SaskatchewanBC Cancer AgencyPrincess Margaret Cancer CentreBrampton Civic HospitalUniversity of TorontoUniversity of British ColumbiaPublic Health Ontario
Fundersnot available
KeywordsMedicinePsychological interventionClinical trialHealth equityDisadvantagedInclusion (mineral)MEDLINEFamily medicineProtocol (science)Alternative medicineGerontologyPublic healthNursingPathology

Abstract

fetched live from OpenAlex

BACKGROUND: The intersection of race and older age compounds existing health disparities experienced by historically marginalised communities. Therefore, racialised older adults with cancer are more disadvantaged in their access to cancer clinical trials compared with age-matched counterparts. To determine what has already been published in this area, the rapid scoping review question are: what are the barriers, facilitators and potential solutions for enhancing access to cancer clinical trials among racialised older adults? METHODS: We will use a rapid scoping review methodology in which we follow the six-step framework of Arksey and O'Malley, including a systematic search of the literature with abstract and full-text screening to be conducted by two independent reviewers, data abstraction by one reviewer and verification by a second reviewer using an Excel data abstraction sheet. Articles focusing on persons aged 18 and over who identify as a racialised person with cancer, that describe therapies/therapeutic interventions/prevention/outcomes related to barriers, facilitators and solutions to enhancing access to and equity in cancer clinical trials will be eligible for inclusion in this rapid scoping review. ETHICS AND DISSEMINATION: All data will be extracted from published literature. Hence, ethical approval and patient informed consent are not required. The findings of the scoping review will be submitted for publication in a peer-reviewed journal and presentation at international conferences.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.168
metaresearch head score (Gemma)0.145
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.832
Threshold uncertainty score0.887

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1680.145
Meta-epidemiology (narrow)0.0050.007
Meta-epidemiology (broad)0.0090.011
Bibliometrics0.0140.012
Science and technology studies0.0060.005
Scholarly communication0.0090.010
Open science0.0070.010
Research integrity0.0100.008
Insufficient payload (model declined to judge)0.0860.023

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.937
GPT teacher head0.830
Teacher spread0.107 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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