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Record W4406147584 · doi:10.1002/cam4.70579

Frequency of Missing <scp>TNM</scp> Stage Data for Adults With Intellectual or Developmental Disabilities in a Provincial Cancer Registry—A Brief Report

2025· article· en· W4406147584 on OpenAlexafffundabout
Kelly Biggs, Hélène Ouellette‐Kuntz, Rebecca Griffiths, Rebecca Hansford, Julie Hallet, Christine Kelly, Kathleen Decker, David E. Dawe, Shahin Shooshtari, Marni Brownell, Donna Turner, Virginie Cobigo, Alyson Mahar

Bibliographic record

VenueCancer Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicDown syndrome and intellectual disability research
Canadian institutionsUniversity of OttawaManitoba HealthSt.AmantResearch ManitobaHealth Sciences CentreCancerCare ManitobaUniversity of ManitobaSunnybrook Health Science CentreQueen's University
FundersCanadian Institutes of Health Research
KeywordsCancer registryMedicineStage (stratigraphy)Psychological interventionPopulationMissing dataConfidence intervalCancerColorectal cancerPediatricsDemographyGerontologyInternal medicineEnvironmental healthPsychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Adults with intellectual or developmental disability (IDD) are at higher risk for incomplete cancer staging. AIM: To compare unknown stage data between those with and without IDD. MATERIALS AND METHODS: We used the Ontario Cancer Registry linked to administrative health data between 2007 and 2019. RESULTS: Adults with IDD diagnosed with breast, colorectal, and lung cancer were 1.94 (95% CI 1.52-2.47), 1.90 (95% CI 1.63-2.21), and 2.17 (95% CI 1.86-2.54) times more likely to have unknown cancer stage at diagnosis, relative to those without IDD. DISCUSSION: The absence of stage data has person-level and population-level implications. At the individual level, if stage data are not simply missing from the registry but reflect incomplete or absent diagnostic or staging procedures, this may represent barriers for adults with IDD in receiving curative treatment. At the population level, research using inaccurate or incomplete stage data may lead to unrepresentative health and social system policy decisions. CONCLUSION: A better understanding of the cancer diagnostic interval for adults with IDD is needed to develop interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.029
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.360
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.029
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.096
GPT teacher head0.398
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes3
Has abstractyes

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