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Record W4407439191 · doi:10.1055/s-0044-1801671

Caplacizumab Added to Plasma Exchange and Immunosuppression Accelerates Recovery and Improves Survival in Immune-Mediated TTP: an International Real-World Study of the IWG-TTP (The Capla 1000+Project)

2025· article· en· W4407439191 on OpenAlexaff
Paul Coppo, Michaël Bubenheim, Y. Benhamou, Linus A. Völker, Paul Brinkkötter, Lucas Kühne, Paul Knöbl, María Eva Mingot‐Castellano, Cristina Pascual, Javier de la Rubia, Julio del Río-Garma, Shruti Chaturvedi, Camila Masias, Marshall Mazepa, X. Long Zheng, György Sinkovits, Marienn Réti, Christopher J. Patriquin, Katerina Pavenski, T Boechat, João Samuel de Holanda Farias, Eduardo Flávio Oliveira Ribeiro, Michaela Larissa Lobo de Andrade, Agnès Veyradier, Bérangère S. Joly, Rachid Bouzid, Kazuya Sakai, Masanori Matsumoto, Pasquale Agosti, Ilaria Mancini, Flora Peyvandi, Eleni Gavriilaki, Matthew Stubbs, Amjad Hmaid, Spero R. Cataland, Bernhard Lämmle, Marie Scully

Bibliographic record

VenueHämostaseologie · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicComplement system in diseases
Canadian institutionsSt. Michael's HospitalUniversity Health Network
Fundersnot available
KeywordsImmunosuppressionMedicineImmunology

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.314
Threshold uncertainty score0.742

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.317
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractno

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