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Record W4409405608 · doi:10.1002/cesm.70026

A New Process Model of Study Identification Specific to the Identification of Randomised Studies for Systematic Reviews of Medical Interventions

2025· article· en· W4409405608 on OpenAlexaff
Chris Cooper, Zahra Premji, Christine Worsley, E. Tomlinson, Sarah Dawson, Emma Prentice

Bibliographic record

VenueCochrane Evidence Synthesis and Methods · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsUniversity of Victoria
FundersNational Institute for Health and Care Research
KeywordsIdentification (biology)Systematic reviewPsychological interventionContext (archaeology)Process (computing)Computer scienceData scienceManagement scienceMEDLINEMedicineEngineering

Abstract

fetched live from OpenAlex

Background: Recent work has illustrated that the same process of study identification is used in systematic reviews irrespective of the studies or data needs required for synthesis. We question if different review types should have their own specific models of study identification, to ensure the appropriate and timely identification of studies/study reports and to minimise research waste. Objective: In this paper, we aim to:1. illustrate and report a new process model to identify randomised studies for systematic reviews of medical interventions; and2. situate the model in context of current practice using a worked example from a recent systematic review. Method: Our model splits the identification of studies from the identification of study reports by searching in distinct phases. It begins with searches of trials registry resources to identify studies, followed by searches of bibliographic databases to identify study reports or unregistered studies. Supplementary search methods are then used to identify unpublished studies. The model includes the possibility of secondary searches, and we consider the role of update searches. Conclusion: A case study illustrates the application of the method alongside operational guidance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.392
metaresearch head score (Gemma)0.558
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.911
Threshold uncertainty score0.626

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.3920.558
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0020.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.787
GPT teacher head0.668
Teacher spread0.119 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designSystematic review
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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