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Record W4409497743 · doi:10.1136/bjsports-2024-109185

Diagnostic domains, differential diagnosis and conditions requiring further medical attention that are considered important in the assessment for Achilles tendinopathy: a Delphi consensus study

2025· article· en· W4409497743 on OpenAlexaff
Peter Malliaras, Karin Grävare Silbernagel, Robert‐Jan de Vos, Jaryd Bourke, Igor Sancho, Shawn L. Hanlon, Anne‐Sofie Agergaard, Roald Bahr, Natália Franco Netto Bittencourt, Marcelo Bordalo Rodrigues, Annelie Brorsson, Victoria Tzortziou Brown, Tanusha Cardoso, S. Child, Ruth L. Chimenti, Emma Cowley, Pieter D’Hooghe, Wayne Derman, Jonathan T. Finnoff, Siu Ngor Fu, Jill Halstead, Bruce Hamilton, Katarina Maria Nilsson-Helander, Per Hölmich, Jonathan Houghton, Alicia M. James, Kornelia Kulig, Amanda Lau, Samuel Ka-Kin Ling, Nicola Maffulli, Lorenzo Masci, Sue Mayes, Seán Mc Auliffe, Carol McCrum, Dylan Morrissey, Shannon E Munteanu, Myles Murphy, Richard Newsham‐West, Seth O’Neill, Nat Padhiar, Theodora Papadopoulou, Jonathan D Rees, Ebonie Rio, Diego Ruffino, Alex Scott, Suzy Speirs, Yang Sun, Kristian Thorborg, Larissa Trease, Jan A.N. Verhaar, Evi Wezenbeek, Susan W. White, Jennifer A. Zellers, Shiping Zhang, Vasileios Korakakis, Bill Vicenzino

Bibliographic record

VenueBritish Journal of Sports Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicTendon Structure and Treatment
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineTendinopathyAchilles tendonTendinosisPhysical therapyDifferential diagnosisMedical diagnosisAnkleBursitisPhysical medicine and rehabilitationTendonSurgeryPathology

Abstract

fetched live from OpenAlex

The absence of agreed methods to diagnose Achilles tendinopathy impedes research and clinical practice. This gap results in heterogeneous and/or poorly described study samples, making it challenging to apply findings in clinical practice. The aim of this Delphi study was to define consensus on (1) diagnostic domains; (2) differential diagnoses; and (3) conditions requiring further medical attention, when assessing for Achilles tendinopathy.We conducted a sequential three-stage process which included: (1) identifying diagnostic domains, differential diagnoses and conditions requiring further medical attention based on existing scoping reviews and clinical practice guidelines; (2) developing Delphi survey questions; and (3) administering a five-round Delphi online survey. Consensus was defined as ≥70% agreement.52 participants completed the surveys. Four diagnostic domains were deemed essential and reached consensus (pain location (93%); pain during activity (97%); tests that provoke pain (87%); palpation to assess pain (83%)). 15 differential diagnoses reached consensus: 2 for both midportion and insertional (partial tear (80%); posterior ankle impingement (78%)), 6 for midportion (plantaris tendinopathy (84%); tibialis posterior or flexor hallucis longus tendinopathy/tenosynovitis (72%); flexor digitorum longus tendinopathy (77%); accessory soleus muscle (74%); paratendinopathy (86%); sural nerve neuropathy (81%)) and 7 for insertional (superficial (88%) and retrocalcaneal bursitis (86%); Haglund's/calcaneal exostosis (80%), intratendinous calcifications (73%); Sever's disease (78%); calcaneal stress reaction/fracture (80%); subtalar/ankle pain (71%)). Six conditions requiring further medical attention reached consensus: (Achilles tendon rupture (83%); systemic inflammatory joint disease (86%); metabolic syndrome (75%); familial hypercholesterolaemia (77%); endocrine and hormonal disorders (80%); drug reactions (77%)).This consensus identified essential diagnostic domains, differential diagnoses and conditions requiring further medical attention that should be considered when assessing for Achilles tendinopathy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.031
Threshold uncertainty score0.570

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.331
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2025
Admission routes1
Has abstractyes

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