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Record W4411439572 · doi:10.1016/j.cjca.2025.06.008

The Trials of Interpreting Clinical Trials—A Bayesian Perspective on Colchicine After an Acute Coronary Syndrome

2025· article· en· W4411439572 on OpenAlexaffvenue
James M. Brophy

Bibliographic record

VenueCanadian Journal of Cardiology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammasome and immune disorders
Canadian institutionsMcGill University Health Centre
Fundersnot available
KeywordsMedicineMacePrior probabilityRandomized controlled trialMyocardial infarctionBayesian probabilityInternal medicineCredible intervalRevascularizationClinical trialRelative riskMeta-analysisCardiologyConfidence intervalConventional PCIStatistics

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.521
metaresearch head score (Gemma)0.804
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.521
Threshold uncertainty score0.590

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.5210.804
Meta-epidemiology (narrow)0.0040.004
Meta-epidemiology (broad)0.0190.006
Bibliometrics0.0070.006
Science and technology studies0.0030.047
Scholarly communication0.0190.020
Open science0.0110.007
Research integrity0.0300.038
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.362
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractno

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