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Record W4411471757 · doi:10.1136/bmjopen-2024-097757

Honest yet unacceptable research practices: when research becomes a health risk

2025· review· en· W4411471757 on OpenAlexaff
Alexander M. Clark, Bailey J. Sousa, Chantal F. Ski, David R. Thompson

Bibliographic record

VenueBMJ Open · 2025
Typereview
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsAthabasca University
Fundersnot available
KeywordsHarmMedicineDishonestyPublic relationsPublic healthBest practiceReputationScientific misconductResearch ethicsAlternative medicinePolitical scienceLawNursingPsychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Examples of poor research practices have received much attention in academic and public arenas. Such practices persist and threaten the health of the public and the reputation and impact of research and researchers. OBJECTIVE: In this article, we argue that research-though intended to improve health-can lead to patient harm through the proliferation of honest (though occasionally dishonest) yet unacceptable research practices. SUMMARY OF KEY ARGUMENTS: We argue that deliberate dishonest research practices-termed questionable research practices-are widely prevalent and insidious and influenced by both individual and cultural factors. Drawing on credible conceptualisations of poor research practices, we define honest yet unacceptable research practices to be different from questionable research practices involving dishonesty, but just as serious due to their wide prevalence and damaging impacts. Finally, we present recommendations for people and organisations to better protect patients' interests from honest yet unacceptable research practices. CONCLUSION: Our recommendations can serve as the basis for preventing honest yet unacceptable poor research practices to safeguard public trust in health professions, researchers and practices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.167
metaresearch head score (Gemma)0.388
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.988
Threshold uncertainty score0.885

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1670.388
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0050.006
Science and technology studies0.0030.028
Scholarly communication0.0120.016
Open science0.0030.009
Research integrity0.0120.013
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.974
GPT teacher head0.849
Teacher spread0.125 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

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