RETRACTED: Non-tuberculous mycobacterial infections among patients with suspected or confirmed pulmonary tuberculosis in Ethiopia: A systematic review and meta-analysis
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Post-publication record
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Abstract
Objectives: This study reviews and analyzes non-tuberculous mycobacteria (NTM) isolation from Ethiopian sputum samples, estimating prevalence, identifying common species, and analyzing regional and temporal variations. Methods: This systematic review and meta-analysis aimed to determine NTM prevalence among diseased individuals in Ethiopia. Using PubMed, Scopus, Web of Science, Google Scholar, and African Journals Online, we conducted a comprehensive literature search. Data extraction and quality assessment were conducted using the Newcastle-Ottawa scale. Meta-analysis was performed using STATA-18 software with a random-effects model and included subgroup analysis. The protocol of this study was registered with PROSPERO (CRD420251000131). Results: In this review, a total of 5415 participants were involved, and 53.8% were patients with suspected tuberculosis (TB), 37.6% were patients with pulmonary TB, 4.0% were patients with multidrug-resistant TB, and 4.6% were HIV-positive patients. The NTM prevalence was 3.8%, showing high heterogeneity and regional species variability. The meta-analysis highlighted differences in NTM prevalence across age groups and diagnostic tools, emphasizing the need for enhanced diagnostics and continuous surveillance to improve patient outcomes and inform public health strategies. Conclusions: The review summarizes the epidemiology and geographical distribution of NTM infections and common NTM species isolated from patients with suspected pulmonary TB in Ethiopia, revealing regional variations and clinical implications. Despite limited data, Ethiopia has a lower prevalence of NTM compared with other African regions and the worldwide average.
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The record
- Venue
- IJID Regions
- Topic
- Mycobacterium research and diagnosis
- Field
- Medicine
- Canadian institutions
- —
- Funders
- University of Gondar
- Keywords
- TuberculosisMedicinePulmonary tuberculosisMeta-analysisMycobacterium InfectionsSystematic reviewIntensive care medicineImmunologyMEDLINEInternal medicinePathologyMycobacteriumBiology
- Has abstract in OpenAlex
- yes