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Effect of Fermentation on <i>In Vitro</i> Protein Digestibility, Physicochemical Properties, and <i>In Vivo</i> Antioxidant Capacity of Hempseed (<i>Cannabis sativa</i> sb. <i>sativa</i>) Added Kombucha

2025· article· en· W4412071309 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueACS Food Science & Technology · 2025
Typearticle
Languageen
FieldMedicine
TopicTea Polyphenols and Effects
Canadian institutionsUniversity of Ottawa
FundersConsejo Nacional de Ciencia y TecnologíaUniversidad de las Américas PueblaUniversity of Ottawa
KeywordsCannabis sativaFermentationAntioxidant capacityFood scienceChemistryIn vivoIn vitroAntioxidantBiochemistryBiotechnologyBotanyBiology

Abstract

fetched live from OpenAlex

High Resolution Image Download MS PowerPoint Slide Kombucha enriched with hempseed showed improved nutritional and functional properties over those of conventional black tea kombucha. This study evaluated the impact of fermentation on the physicochemical characteristics and protein digestibility of hempseed kombucha in fermented (K f, HK f ) and unfermented (K u, HK u ) forms, along with a hempseed water extract (HE). Samples were analyzed for protein profile (SDS-PAGE), particle size and polydispersity (DLS), surface hydrophobicity (ANS), and in vitro protein digestibility (OPA assay). Antioxidant activity was assessed using in vitro (DPPH+, ABTS+, and FRAP) and in vivo ( Caenorhabditis elegans ) methods. Fermentation significantly increased protein content and antioxidant capacity ( p < 0.05), especially in hempseed-containing samples. SDS-PAGE identified unique bands: 43 (HE), 20 (K f ), and 40 kDa (HK f ). Fermentation increased particle size and reduced hydrophobicity ( p < 0.05), while HE and HK u had the highest hydrophobicity. Protein hydrolysis was 34.6% higher in HK f than HK u ( p < 0.05). These results highlight fermented hempseed kombucha as a promising functional plant-based beverage.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.858

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.003
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.256
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it