MétaCan
Menu
Back to cohort
Record W4414514051 · doi:10.1093/ajcp/aqaf109

Underfilled tubes revisited: What blood tests can be reported on short draws?

2025· article· en· W4414514051 on OpenAlexaff
Lawrence de Koning, Sally Ezra, Fangze Cai, Isolde Seiden‐Long, Tariq Roshan, Jessica L. Gifford, Albert K.Y. Tsui

Bibliographic record

VenueAmerican Journal of Clinical Pathology · 2025
Typearticle
Languageen
FieldMedicine
TopicClinical Laboratory Practices and Quality Control
Canadian institutionsUniversity of AlbertaCalgary Laboratory ServicesFoothills Medical CentreHealth Sciences CentreMD Precision (Canada)University of Calgary
Fundersnot available
KeywordsHematologic testsHematologyHematology analyzerPoint-of-care testingHemagglutination tests

Abstract

fetched live from OpenAlex

OBJECTIVE: Underfilled blood tubes (short draws) are often collected from children or those with poor venous access. In a pilot study, we investigated which tests among a large acute care panel could be reported on short draws. METHODS: Blood was drawn in BD vacutainers (short draw: 1 mL [33%-56% fill volume] vs complete draw: 1.8-3 mL [100% fill volume]) from 12 volunteers for 3 coagulation tests, 36 chemistry tests, and the complete blood count (CBC) with differential. Tests that were strong candidates for reporting did not have statistically significant biases between short and complete draws, whereas potential candidates had statistically significant biases that were small (<25% of total allowable error and less than desirable bias from biological variation). Biases that increased or decreased across concentration ranges invalidated reporting candidacy. RESULTS: Two coagulation tests, 14 chemistry tests, and 15 CBC components were strong candidates for reporting. There were 9 chemistry tests and 2 CBC components that were potential candidates for reporting. CONCLUSIONS: Underfilled blood tubes, or short draws, may be valid collections for several coagulation, chemistry, and hematology tests-which may prevent additional unnecessary phlebotomy. Laboratories should perform their own studies to determine if short draws are acceptable for limited testing using their tube and instrument types.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.031
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.376
Threshold uncertainty score0.978

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.031
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.479
Teacher spread0.384 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueAmerican Journal of Clinical PathologySame topicClinical Laboratory Practices and Quality ControlFrench-language works237,207