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Record W4414518974 · doi:10.1016/j.eururo.2025.08.019

A Multicenter Randomized Controlled Trial of Antimicrobial Prophylaxis to Prevent Urinary Tract Infections after Shockwave Lithotripsy for Urolithiasis: The APPEAL Trial

2025· article· en· W4414518974 on OpenAlexafffund
Kari A.O. Tikkinen, Borna Tadayon Najafabadi, Sakineh Hajebrahimi, Farhad Tondroanamag, Arto Mikkola, Saana Horstia, Patrick O. Richard, Sara Tornberg, Mohamed Abdelkareem, Le Mai Tu, Thomas Tailly, Farzin Soleimanzadeh, Hanieh Salehi‐Pourmehr, Mari Saalasti, Jani Ruotsalainen, Hassan Razvi, Negar Pourjamal, Stephen E. Pautler, Niko K Nordlund, Sanna Myrskysalo, Andrey Morozov, Mohsen Mohammadrahimi, Murilo Luz, Samuel Lagabrielle, Pauliina Kuutti, Tuomas P. Kilpeläinen, Petrus Järvinen, Alex L E Halme, Agus Rizal Ardy Hariandy Hamid, D. S. Gorelov, Pramila Gaudel, Nariman Gadzhiev, John D. Denstedt, Kathrin Bausch, Raed A. Azhar

Bibliographic record

VenueEuropean Urology · 2025
Typearticle
Languageen
FieldMedicine
TopicKidney Stones and Urolithiasis Treatments
Canadian institutionsWestern UniversityCentre Hospitalier Universitaire de SherbrookeUniversité de SherbrookeMcMaster University
FundersSigrid Juséliuksen SäätiöAcademy of FinlandPhysicians' Services Incorporated FoundationLawson Health Research InstituteHelsingin ja Uudenmaan Sairaanhoitopiiri
KeywordsRandomized controlled trialAbsolute risk reductionAntibiotic prophylaxisUrinary systemAntimicrobialCiprofloxacinReduction (mathematics)Multicenter trial

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.037
Threshold uncertainty score0.873

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.286
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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