MétaCan
Menu
Back to cohort
Record W4414620780 · doi:10.37044/osf.io/wj8bz_v1

Translating and Formalizing the MIRAGE Guidelines to a Prototype MIRAGE Ontology and DCAT3 Extension Vocabulary for Glycomics Data Management

2025· preprint· en· W4414620780 on OpenAlexfundno aff
Achille Zappa

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiomedical Text Mining and Ontologies
Canadian institutionsnot available
FundersNational Bioscience Database CenterCanadian Glycomics NetworkJapan Science and Technology AgencyMinistry of Education, Culture, Sports, Science and Technology
KeywordsGlycomicsOntologySemantic WebMetadataRDFStandardizationControlled vocabularyVocabularyInteroperability

Abstract

fetched live from OpenAlex

The Minimum Information Required for A Glycomics Experiment (MIRAGE) guidelines haveestablished comprehensive reporting standards for glycomics research, yet their implementationin semantic web technologies remains limited. We present the first comprehensive semanticformalization of MIRAGE guidelines through an integrated RDF ontology framework comprising the MIRAGE Ontology and MIRAGE-DCAT3 vocabulary. The MIRAGE Ontologymodels glycan structures, biological specimens, analytical instruments, and experimental processes with formal OWL semantics and SHACL validation constraints. The complementaryMIRAGE-DCAT3 vocabulary extends W3C DCAT3 with glycomics-specific metadata propertiesfor dataset cataloging and discovery. Our implementation addresses critical challenges inglycomics data interoperability through comprehensive mappings to established ontologiesincluding GlycoRDF, PSI-MS, and DCTERMS. This semantic framework enables automatedquality assessment, federated data querying, and enhanced reproducibility in glycomics research, supporting broader adoption of FAIR principles in the glycobiology community. Theframework demonstrates comprehensive coverage of MIRAGE reporting requirements acrossmultiple analytical platforms including mass spectrometry, liquid chromatography, capillaryelectrophoresis, NMR spectroscopy, and lectin microarray analysis

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.990
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.011
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.003
Bibliometrics0.0030.002
Science and technology studies0.0020.002
Scholarly communication0.0060.007
Open science0.0030.005
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0050.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.123
GPT teacher head0.393
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainReporting
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same topicBiomedical Text Mining and OntologiesFrench-language works237,207