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Record W4414625223 · doi:10.1016/j.jcjo.2025.09.004

The growing presence of AI-generated content in ophthalmology: a retrospective bibliographic analysis

2025· article· en· W4414625223 on OpenAlexaffvenue
Michael Balas, Xiaole Li, Parnian Arjmand

Bibliographic record

VenueCanadian Journal of Ophthalmology · 2025
Typearticle
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsContent analysisContent (measure theory)MEDLINEScientific literatureBibliometrics

Abstract

fetched live from OpenAlex

OBJECTIVE: To quantify the prevalence and trends of artificial intelligence (AI)-generated content in ophthalmology manuscripts, particularly following the public release of OpenAI's ChatGPT on November 30, 2022. METHODS: A retrospective bibliographic analysis was conducted on 1 036 manuscripts from 30 ophthalmology journals, divided into pre-December 2022 (519 manuscripts) and post-December 2022 (517 manuscripts) periods. AI-generated content was evaluated using the Originality Standard 2.0.0 model, which calculates AI probability scores (AIPS) ranging from 0% to 100%. Readability metrics (e.g., Flesch-Kincaid Score) and journal impact metrics (e.g., impact factor) were analyzed. RESULTS: AIPS remained stable from 2014 to 2022 but increased significantly after December 2022 (p < 0.001). The mean AIPS rose from 4.95% in 2022 to 11.2% by mid-2024, with projections estimating 17.51% by mid-2026. Editorials exhibited the highest mean AIPS (12.8%), while surgical technique studies had the lowest (4.33%). Higher AIPS were associated with lower journal impact factors (Spearman's ρ = -0.54; p < 0.001) and simpler language, as reflected by lower Automated Readability Index scores (Spearman's ρ = -0.12; p < 0.005). None of the included manuscripts disclosed AI usage, including 44 manuscripts with AIPS exceeding 25%. CONCLUSIONS: AI-generated content in ophthalmology has risen significantly since ChatGPT's release. Higher AIPS correlates with lower journal impact factors and reduced literary complexity. The lack of AI usage disclosure raises ethical concerns and emphasizes the need for transparent reporting and guidelines to ensure the integrity of scientific research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.065
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Bibliometrics
Consensus categoriesnone
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.990
Threshold uncertainty score0.055

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.065
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0350.035
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.002
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.404
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designObservational
DomainEvaluation
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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