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Comparación entre un método semiautomático y una búsqueda tradicional para la identificación de estudios que informen recomendaciones de guías de práctica clínica GES: Un estudio metaepidemiológico

2025· article· en· W4414686899 on OpenAlexaff
Camila Ávila, Francisca Verdugo‐Paiva, Gonzalo Bravo‐Soto, Gabriel Rada, Ignacio Neumann

Bibliographic record

VenueRevista médica de Chile · 2025
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcMaster UniversityImpact
Fundersnot available
KeywordsContext (archaeology)Identification (biology)Process (computing)Work (physics)Systematic review

Abstract

fetched live from OpenAlex

Recently, there has been a surge in technological tools designed to automate tasks across various areas of health sciences, including the identification of evidence used in the development of evidence syntheses that inform clinical practice guideline (CPG) recommendations. Simultaneously, there has been a significant increase in the production of systematic reviews, meaning that much of the relevant evidence is already included in existing reviews. AIM: To compare the performance of the semi-automated Epistemonikos Evidence Matrix tool with that of a traditional manual literature search in identifying studies for the development of clinical practice guidelines. MATERIALS AND METHODS: During the development of three CPGs (focused on HIV/AIDS, pediatric asthma management, and stroke management), we compared studies identified through a traditional search strategy in MEDLINE, Embase, and the Cochrane Library with those found using a strategy based on existing systematic reviews, via the Epistemonikos database. The traditional search employed keyword-based strategies and a specific filter for randomized controlled trials. In contrast, the Epistemonikos-based strategy relied on the semi-automated Evidence Matrix tool, which identifies studies shared across two or more systematic reviews. RESULTS: Across the three guidelines, 8,466 potentially relevant articles were identified using the traditional method, compared to 6,771 using the Epistemonikos-based method. Of these, 155 studies (1.8%) were deemed truly relevant in the traditional search, versus 103 (1.5%) in the Epistemonikos-based approach (p= 0.14). The approach based on existing reviews demonstrated significantly higher precision (94% vs. 78%, p<0.01) but lower sensitivity (58% vs. 88%, p<0.01) compared to the traditional search. CONCLUSIONS: The evidence search strategy based on existing systematic reviews is an efficient and reliable alternative for identifying relevant studies to support evidence-based decision-making.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.408
metaresearch head score (Gemma)0.690
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Meta-epidemiology (broad)
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: Methods
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.995
Threshold uncertainty score0.730

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.4080.690
Meta-epidemiology (narrow)0.0050.005
Meta-epidemiology (broad)0.0090.014
Bibliometrics0.0410.029
Science and technology studies0.0020.004
Scholarly communication0.0150.012
Open science0.0070.010
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.322
GPT teacher head0.481
Teacher spread0.159 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designMeta-analysis
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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