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Record W4415259594 · doi:10.1093/jamiaopen/ooaf122

ECG-FM: an open electrocardiogram foundation model

2025· article· en· W4415259594 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJAMIA Open · 2025
Typearticle
Languageen
FieldMedicine
TopicECG Monitoring and Analysis
Canadian institutionsVector InstituteUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsFoundation (evidence)Benchmark (surveying)Model validationMathematical model

Abstract

fetched live from OpenAlex

Objectives: To develop ECG-FM, an open-weight foundation model for electrocardiogram (ECG) analysis, rigorously evaluate its performance on clinically salient tasks, and openly release it alongside a public benchmark. Materials and Methods: In a study using 1.5 million 12-lead ECGs, we present ECG-FM, a transformer-based foundation model pretrained with hybrid self-supervision that combines masked reconstruction and contrastive learning with ECG-specific augmentation. Downstream, we evaluate multi-label ECG interpretation and prediction of reduced left ventricular ejection fraction (LVEF), introducing an openly available benchmark on the MIMIC-IV-ECG dataset. We assess ECG-FM's capabilities through data scaling experiments, latent-space structure analysis, and attention-based saliency. Results: (0.929). The pretrained encoder showcases competitive linear probing performance, with functionally discriminative embeddings. Discussion: Findings indicate that ECG-FM is generalizable, label-efficient, and discriminative for screening, risk stratification, and monitoring. Its representations capture low-level morphology and high-order cardiac semantics, and the pretrained encoder serves as a robust feature-set generator. This work mitigates reliance on large labeled datasets, reduces compute and data requirements, and lowers barriers to reproducibility and cross-study comparison. Conclusion: ECG-FM is an open, rigorously validated ECG foundation model intended to accelerate transparent, comparable research in the ECG analysis subfield. It is designed for rapid integration and evaluation, especially for delivering practical gains in low-label settings. We release our code, model weights, tutorials, and benchmark at https://github.com/bowang-lab/ECG-FM/.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.845
Threshold uncertainty score0.420

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.411
Teacher spread0.369 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it