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Record W4415536077 · doi:10.1016/j.eclinm.2025.103586

Identifying Social factors that Stratify Health Opportunities and Outcomes (ISSHOOs) in pain research: consensus recommendations for the collection and reporting of equity-relevant data

2025· article· en· W4415536077 on OpenAlexafffundabout
Emma L. Karran, Aidan G Cashin, Alessandro Chiarotto, Saurab Sharma, Trevor Barker, Mark Boyd, Lara Maxwell, Vina Mohabir, Jennifer Petkovic, Peter Tugwell, G. Lorimer Moseley, Oluwafemi K Ajayi, Ruth Appiah, Cheryl Barnabé, Sónia F. Bernardes, Didier Bouhassira, Margarita Calvo, Mary Cowern, Bróna M. Fullen, Catherine Hofstetter, Mary R. Janevic, Flavia P. Kapos, Dale J. Langford, Bronwyn Lennox–Thompson, John D. Loeser, Tonya M. Palermo, Romy Parker, Karma Phuentsho, Andrew S.C. Rice, Sinan Tejani, Rolf‐Detlef Treede, Janice Tufte

Bibliographic record

VenueEClinicalMedicine · 2025
Typearticle
Languageen
FieldMedicine
TopicMusculoskeletal pain and rehabilitation
Canadian institutionsInstitute for Clinical Evaluative SciencesSickKids FoundationHealth CanadaOttawa HospitalHospital for Sick ChildrenUniversity of Ottawa
FundersHORIZON EUROPE European Innovation CouncilNational Health and Medical Research CouncilZonMwInternational Association for the Study of PainCanada Excellence Research Chairs, Government of CanadaMAYDAY Fund
KeywordsData collectionMEDLINESocial mediaPublic healthHealth professionalsHorizon

Abstract

fetched live from OpenAlex

Background: The aspiration to improve health equity is fundamental to scholarly focus and action in public health, and highly relevant to addressing the global burden of pain-the leading contributor to disability worldwide. There is potential for advancement towards health equity to be facilitated by greater access to data that identifies the role of socio-demographic factors in pain and health outcomes. Methods: The 'Identifying Social factors that Stratify Health Opportunities and Outcomes (ISSHOOs) in Pain Research' project was a multi-stage process that aimed to reach consensus on the most important equity-relevant items to include in all human adult pain research. Conducted April 2022-May 2025, it incorporated two scoping reviews (published 2023), an international Delphi study (published 2025), consensus meetings and focus groups; prioritising global participation, patient perspectives, and interdisciplinary expertise throughout. Findings: Three hundred and four individuals from 45 countries, across six continents, contributed to developing two sets of items. Set A, the 'minimum dataset', is a globally relevant set of eight standardised socio-demographic items (age, sex, gender identity, place, race/ethnicity/cultural identity, education, financial position, work status), accompanied by concise guidance to assist implementation and setting-specific tailoring; Set B is an 'extended dataset' of optional items from which researchers can select items consistent with their study population and research questions. The ISSHOOs recommendations offer a culturally sensitive, cross-culturally relevant, practical and highly useful resource. Interpretation: Routine adoption and clear reporting of the ISSHOOs datasets across all human adult pain research will lead to improved and harmonious descriptions of research participants across health equity domains. Our goal is to promote equity-relevant awareness and understanding, and ultimately drive progress towards reducing avoidable disparities in health for people with pain, with potential for broader application to other fields of health. Funding: NHMRC (Australia); MAYDAY Fund; IASP; Canada Research Chair Program; European Horizon 2020 Research and Innovation Programme; ZonMw programs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.027
metaresearch head score (Gemma)0.036
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.464
Threshold uncertainty score0.972

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0270.036
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.737
GPT teacher head0.597
Teacher spread0.140 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes3
Has abstractyes

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