MétaCan
Menu
Back to cohort
Record W4416418362 · doi:10.1016/j.jisako.2025.101035

Combined high tibial osteotomy and root repair improves patient-reported outcomes in medial meniscus posterior root tears: A systematic review and meta-analysis

2025· article· en· W4416418362 on OpenAlexaff
Ayomide Michael Ade‐Conde, Michelle Cruickshank, Marc Daniel Bouchard, Prushoth Vivekanantha, Amit Meena, Shahbaz S. Malik

Bibliographic record

VenueJournal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicKnee injuries and reconstruction techniques
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedial meniscusHigh tibial osteotomyOsteotomyRoot (linguistics)Meniscus

Abstract

fetched live from OpenAlex

Importance High tibial osteotomy (HTO) is a well-established joint-preserving surgery for varus knees with medial compartment overload. There is a growing interest in combining HTO with meniscal root repair (HTO-MRR) to address both the varus malalignment and the meniscal deficiency caused by medial meniscus posterior root tears (MMPRTs). Aim This systematic review and meta-analysis aimed to synthesise current evidence on the clinical, radiographic, and arthroscopic outcomes following HTO-MRR for isolated MMPRTs. Where available, comparative data with HTO alone were analysed as a secondary objective. Evidence review MEDLINE, EMBASE, and CINAHL were searched from inception to June 5, 2025 for studies on HTO-MRR for isolated MMPRTs. Data from comparative studies with HTO alone were pooled using random-effects models. Outcomes included patient-reported outcomes (PROMs), range of motion, radiographic parameters, and healing rates. Findings Thirteen studies, comprising 725 patients with degenerative MMPRTs (67% female), met the inclusion criteria. Of these, 459 underwent HTO-MRR and 266 underwent HTO alone. The mean age was 54 ​± ​9 years (range, 41–65) and a mean follow-up of 25 months (range, 15–66). The baseline varus angles in HTO-MRR patients ranged from 3.3° ​± ​1.2°–6.9° ​± ​2.5°. Weighted means for postoperative Lysholm, Hospital for Special Surgery (HSS), and International Knee Documentation Committee (IKDC) scores were 86 (range, 78–95), 85 (range, 81–85), and 68 (range, 50–81), respectively. The minimal clinically important difference (MCID) thresholds of 8.9, 5.4, and 12.5 for these PROMs, respectively, were exceeded. There was a statistically significant improvement in HSS (standardised mean difference [SMD]: 0.59; 95% CI 0.34–0.84; I 2 ​= ​0%; p ​< ​0.01) and IKDC scores (SMD: 0.31; 95% CI 0.01–0.61; I 2 ​= ​0%; p ​= ​0.04) in HTO-MRR versus HTO alone. Complete meniscal healing rates following HTO-MRR ranged from 13% to 60%, with a weighted mean of 33%. Radiographic parameters, including Kellgren–Lawrence grade, meniscal extrusion, and joint space width, showed no statistically significant between-group differences (all p ​> ​0.05). Conclusion and Relevance HTO-MRR demonstrated improved HSS and IKDC scores compared to HTO alone in isolated MMPRTs. While no short-to mid-term differences in osteoarthritic progression were observed, the current level of evidence remains low, and the potential joint-preserving benefits of HTO-MRR warrant investigation in long-term prospective studies. Level of Evidence IV.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.633
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0070.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.272
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of ISAKOS Joint Disorders & Orthopaedic Sports MedicineSame topicKnee injuries and reconstruction techniquesFrench-language works237,207