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Record W4416598529 · doi:10.1186/s13063-025-09260-4

Shared decision-making and behaviour change collide: an analysis of consultations discussing clinical trial recruitment

2025· article· en· W4416598529 on OpenAlexafffund
A. M. Stephen, Ayodeji Matuluko, Kelly Carroll, Taylor Coffey, Louisa Lawrie, Frances Sherratt, Natasha Hudek, Fabianna Lorencatto, Justin Presseau, Susan Marlin, Dawn P. Richards, Jamie Brehaut, Katie Gillies

Bibliographic record

VenueTrials · 2025
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsRobarts Clinical TrialsUniversity of OttawaOttawa Hospital
FundersMedical Research CouncilCanadian Institutes of Health Research
KeywordsBehaviour changeClinical trialAlternative medicineMEDLINEResearch designOutcome (game theory)Randomized controlled trial

Abstract

fetched live from OpenAlex

BACKGROUND: Recruitment to clinical trials is often challenging, and evidence on effective recruitment strategies remains limited. Framing trial recruitment as a behaviour, amenable to change, enables the application of behavioural science frameworks to better understand and potentially improve recruitment processes. Since trial participation is also a preference-sensitive decision, shared decision-making (SDM) may further enhance ethical recruitment. The present study aimed to explore how behavioural taxonomies and SDM frameworks can be applied to recruitment consultations to identify behaviour change techniques (BCTs) and assess the extent of SDM. METHODS: A secondary analysis was conducted on 53 audio-recorded consultations; consultations from 3 trials in oncology and gastroenterology were sampled. The action, actor, context, target, and time (AACTT) framework was used to define recruitment behaviours, which were then coded using the Behaviour Change Technique Taxonomy v1 (BCTTv1). SDM was assessed using the 5-item 'Observing Patient Involvement' (OPTION5) tool, which evaluates patient involvement in decision-making. Descriptive statistics and frequency counts were used to analyse the data. RESULTS: Twenty-one of the 93 BCTs in the BCTTv1 were identified across all consultations. The most frequently coded BCTs were 5.1 (information about health consequences) and 5.3 (information about social and environmental consequences), both present in all consultations. No substantial difference in the total number of BCTs was observed between trial consenters (M = 6.8, SD = 1.5) and decliners (M = 6.4, SD = 2.1). However, some techniques showed variability: BCT 7.1 (prompts and cues) appeared more frequently in consultations with consenters (84%) than decliners (38%), while BCT 1.4 (action planning) was more frequent in decliners (44%) than consenters (27%). SDM, as measured by OPTION5, was low overall, with a mean score of 27.7 (SD = 12.2) out of 100, with no significant differences across trials or participant groups. CONCLUSIONS: This study demonstrates the feasibility of applying behavioural science and SDM frameworks to analyse trial recruitment consultations. While a range of BCTs were identified, SDM efforts were generally low. Recruitment practices may benefit from more deliberate consideration of these techniques and greater emphasis on shared decision-making to support informed choices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.034
metaresearch head score (Gemma)0.238
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.530
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0340.238
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.901
GPT teacher head0.741
Teacher spread0.160 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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