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Record W7117077043 · doi:10.1016/s1470-2045(25)00535-2

International consensus recommendations and alignment of terminology for the histopathological diagnosis of extranodal extension in head and neck squamous cell carcinoma: an HN-CLEAR initiative

2025· article· en· W7117077043 on OpenAlexaff
Ruta Gupta, Timothy Fielder, Munita Bal, Simion I. Chiosea, Jane E. Dahlstrom, Aanchal Kakkar, Katalin Kiss, Ján Laco, Neha Mittal, Sunil Pasricha, Spinder Samra, Nina Zidar, Martin Bullock, Rebecca D. Chernock, William Faquin, M Richardson, D Neil Hayes, Sicong Huang, Jean A. Yang, Ziyad Alsugair, N. Benzerdjeb, Shaun Chou, Caroline Cooper, Katarina Dimnik, Rimlee Dutta, Ricardo Santiago Gomez, Juan C. Hernandez‐Prera, Meenakshi Kamboj, Tina Klitmøller Agander, Ankur Kumar, Jenny T. H. Lee, Diana Bell, Toshitaka Nagao, Masato Nakaguro, Timothy Onyuma, Ji Hyun Park, Jin Woo Park, Asawari Patil, Miroslav Podhola, Swapnil Rane, Sean A. Rasmussen, Tomáš Rozkoš, Prarthna Shah, Divakar Sharma, Stefi Stefi, Antje Johanne Katrine Stubsgaard, Ana Cristina Tetzner, Bruce M. Wenig, William H Westra, Laura Wise, Sun Och Yoon, Justin A Bishop, Keith D. Hunter, K. Magliocca, R Seethala, Lester D R Thompson, Ilan Weinreb, Peter Angelos, Beth M. Beadle, R Bryan Bell, Jonathan R Clark, Robert Ferris, Rahul Ladwa, James S. Lewis

Bibliographic record

VenueThe Lancet Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicHead and Neck Cancer Studies
Canadian institutionsUniversity Health NetworkUniversity of TorontoPrincess Margaret Cancer CentreDalhousie University
FundersNational Health and Medical Research Council
KeywordsTerminologyHead and neckConcordanceHead and neck cancerSquamous cell cancerMEDLINE

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.238
metaresearch head score (Gemma)0.228
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.238
Threshold uncertainty score0.940

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2380.228
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0040.010
Bibliometrics0.0150.012
Science and technology studies0.0040.006
Scholarly communication0.0100.006
Open science0.0160.010
Research integrity0.0110.021
Insufficient payload (model declined to judge)0.0030.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.385
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractno

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