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Record W7117326365 · doi:10.1002/alz70858_106045

Inequities in dementia risk and recommandations for inequity stratifiers collection in research

2025· article· en· W7117326365 on OpenAlexaffabout
Stefanie A Tremblay, Vasvi Dhir, Isabel McDonald, Juhi Tulsi, Laurence J. Kirmayer, Martin Guhn, Nancy E. Mayo, Maiya R. Geddes

Bibliographic record

VenueAlzheimer s & Dementia · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsUniversité de MontréalMcGill UniversityNeuroRx Research (Canada)Montreal Neurological Institute and Hospital
Fundersnot available
KeywordsDementiaEthnic groupDelphi methodData collectionInclusion (mineral)Best practiceHarmonizationPopulationGeneral partnership

Abstract

fetched live from OpenAlex

Abstract Certain communities, including ethnic and cultural minorities, experience disproportionately higher rates of dementia and worse outcomes. 1,2 Structural and social determinants of health (SSDH)—the conditions in which people are born, live, work, and age 3 —are likely key drivers of these disparities. 4 The effects of SSDH accumulate over the lifecourse, influencing physical, mental, and brain health, as well as the ability to adopt healthy behaviors. 4 Despite growing recognition of their role in dementia inequities, SSDH remain inconsistently integrated into research, and Canada lacks specific guidelines for their inclusion in dementia studies. This project seeks to provide clear guidance for integrating SSDH into aging and dementia research in Canada. In collaboration with a network of stakeholders and knowledge users, we are developing a recommendation framework grounded in community and expert input. To ensure a comprehensive approach, we are 1) Engaging community partners (e.g., individuals with lived experience, advocates for marginalized communities) through mind mapping sessions to identify the factors they view as most critical to maintaining brain health in aging. 2) Conducting a Delphi survey that invites both field experts and community partners to prioritize key SSDH indicators. 3) Reviewing current practices for assessing SSDH in Canadian longitudinal studies on dementia and aging through a scoping review, the findings of which will further inform the recommendations. The resulting guidance framework will be shared as an online toolkit to facilitate its adoption and promote harmonization across Canadian cohorts. To support implementation, workshops and webinars will be organized to help researchers integrate SSDH into all stages of their work, from data collection to analysis and interpretation. Adopting a harmonized SSDH battery across Canadian cohorts will enable the generation of large, pooled datasets, allowing for robust investigations of SSDH variables and their interactions. Although this initiative is tailored to the Canadian context, we hope it can serve as a model for other countries and be adapted to address dementia‐related inequities worldwide. References 1. Lee et al. JAMA Network Open . 2022;5. 2. Mukadam et al. Int. J. Geriatr. Psychiatry . 2011;26. 3. Gómez et al. JPHMP . 2021;27. 4. Adkins‐Jackson et al. A&D . 2023;19.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score0.993

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.375
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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