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Record W7117573235 · doi:10.1186/s12889-025-25402-4

Defining a public health approach to substance use: insights from a systematic scoping review and conceptual framework development approach

2025· article· en· W7117573235 on OpenAlexafffund
Holly Mathias, Nicole D. Gehring, R. Marcus Hammond, Javiera Navarrete, Jean-François Crépault, Brian Emerson, Anna Markov, Brynn Kosteniuk, Kelsey A. Speed, Ethan Candler, Garrison J. B. Dyck, Lexis R. Galarneau, Tariq Z. Issa, Juan Carlos Ocampo Alvarado, Sandy Campbell, Elaine Hyshka

Bibliographic record

VenueBMC Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicSubstance Abuse Treatment and Outcomes
Canadian institutionsUniversity of AlbertaCapital District Health AuthorityToronto Public HealthCentre for Addiction and Mental HealthUniversity of TorontoRoyal Alexandra HospitalAlberta Health Services
FundersCanadian Public Health AssociationKillam TrustsCanada Research ChairsPierre Elliott Trudeau Foundation
KeywordsPublic healthConceptual frameworkPsychological interventionBiostatisticsHarmPublic health interventionsSystematic reviewHealth policy

Abstract

fetched live from OpenAlex

BACKGROUND: Psychoactive substance use represents a significant global public health challenge, leading to diverse health, social, and environmental harms. Traditional punitive and commercial approaches have faced criticism for potentially worsening these harms and overlooking potential benefits. Consequently, there is an increasing global call for a comprehensive public health approach to address psychoactive substances, focusing on both supply and demand reduction. However, the core components of a public health approach remain unclear. We aimed to conceptualize a public health approach to psychoactive substances and describe its core values, goals, and activities. METHODS: We used a two-step process to develop a coherent and comprehensive conceptual framework. First we conducted a scoping review of academic and practice literature on a public health approach to psychoactive substances published between 1950 and 2023 (n = 230 English language records). We then conducted an iterative team-based synthesis of the review findings and expert public health knowledge to address gaps in extant literature using a structured conceptual framework development approach. RESULTS: This conceptual framework includes core values (i.e. social justice, health equity, evidence-informed), activities (i.e. legal and regulatory action, supports and services, prevention and education, advocacy, and research, monitoring, and evaluation), and goals (e.g. improving population health; addressing determinants of substance use, substance harms and substance policy related harms; countering carceral logics) that are central to a public health approach to psychoactive substances. CONCLUSIONS: Our coherent and comprehensive framework incorporates international literature and is informed by contemporary values and goals with the aim of promoting a consensus understanding of this critical practice area. This framework can guide efforts to design, implement, and evaluate public health interventions that maximize benefits and mitigate harm associated with psychoactive substances.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.213
metaresearch head score (Gemma)0.248
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.213
Threshold uncertainty score0.971

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2130.248
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0040.007
Bibliometrics0.0650.049
Science and technology studies0.0070.014
Scholarly communication0.0190.019
Open science0.0060.016
Research integrity0.0070.007
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.352
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

Explore more

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