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Record W7118096213 · doi:10.1093/geroni/igaf122.4061

Advancing Dementia Research in Canada: Early Insights From a Scoping Review of Reviews

2025· article· en· W7118096213 on OpenAlexaffabout
Juanita-Dawne Rena Bacsu, Kiana Mero, Alixe Ménard, Megan E O’Connell, Jennifer Bethell, Sarah Fraser, Sheila Blackstock, Wendy Hulko

Bibliographic record

VenueInnovation in Aging · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsUniversity of SaskatchewanUniversity of OttawaUniversity Health NetworkThompson Rivers University
Fundersnot available
KeywordsDementiaSystematic reviewQuality of life (healthcare)Health carePresentation (obstetrics)MEDLINE

Abstract

fetched live from OpenAlex

Abstract Recently, a national dementia strategy was developed to advance the field of brain health and dementia in Canada. However, there is a paucity of information on the current research landscape and evidence available to advance this strategy. Drawing on findings from our recent scoping review of reviews, this late breaking presentation aims to: i) identify the landscape of Canadian-led reviews on brain health and dementia research; and 2) recognize knowledge gaps and areas of innovation to strengthen brain health and dementia research, policy, and practice. Drawing on Arksey and O’Malley’s framework, a comprehensive scoping review protocol was developed which guided our search of five databases (CINAHL, PubMed, PsycINFO, Scopus, and Web of Science). The literature was independently screened by two reviewers, extracted into a standardized table, and thematically analyzed. We found a total of 7860 initial articles, with 275 reviews included in our analysis. Findings were identified in three areas: 1) risk reduction strategies related to modifiable risks, lifestyle choices, and pharmacological factors; 2) enhancing therapies and finding a cure ranging from neuroimaging techniques to biomedical research; and 3) enhancing the quality of life of people living with dementia and care partners using a range of strategies to improve mental, social, and physical aspects. Although extensive reviews exist, significant knowledge gaps remain driven by factors such as limited participant diversity, inconsistent measures, and lack of targeted coordination, among other challenges. Findings from this study reveal vital gaps and research priorities that are essential to advancing Canada’s dementia strategy forward.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.071
metaresearch head score (Gemma)0.217
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.929
Threshold uncertainty score0.816

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0710.217
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0050.004
Bibliometrics0.0470.077
Science and technology studies0.0040.003
Scholarly communication0.0130.006
Open science0.0030.006
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.419
Teacher spread0.360 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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