Whole genomes redefine the mutational landscape of pancreatic cancer
2015· article· en· Nature· Medicine
affno abstract
2,673
citations
Works
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1,206 workspage 1 of 49
Comprehensive genomic profiles of small cell lung cancer
2015· article· en· Nature· Medicine
affno abstract
2,386
citations
The Life History of 21 Breast Cancers
2012· article· en· Cell· Biochemistry, Genetics and Molecular Biology
aff
1,532
citations
DNA Damage Sensing by the ATM and ATR Kinases
2013· review· en· Cold Spring Harbor Perspectives in Biology· Biochemistry, Genetics and Molecular Biology
fundno aff
1,505
citations
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
2010· article· en· Nature· Medicine
affno abstract
1,324
citations
1,181
citations
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
2004· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
1,159
citations
Hypoxia, DNA repair and genetic instability
2008· review· en· Nature reviews. Cancer· Biochemistry, Genetics and Molecular Biology
affno abstract
1,131
citations
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
2012· article· en· Nature· Biochemistry, Genetics and Molecular Biology
afffund
921
citations
Repeat instability: mechanisms of dynamic mutations
2005· article· en· Nature Reviews Genetics· Neuroscience
affno abstract
914
citations
APOBEC3B is an enzymatic source of mutation in breast cancer
2013· article· en· Nature· Medicine
fundno affno abstract
876
citations
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
2012· article· en· Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
868
citations
Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
2012· article· en· British Journal of Cancer· Medicine
aff
852
citations
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
2020· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
aff
774
citations
The control of DNA repair by the cell cycle
2016· review· en· Nature Cell Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
753
citations
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer
2018· article· en· Cell· Medicine
affno abstract
748
citations
Molecular landmarks of tumor hypoxia across cancer types
2019· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
affno abstract
717
citations
Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
2018· article· en· Cancer Cell· Medicine
affno abstract
710
citations
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
2009· review· en· Biochemical Journal· Biochemistry, Genetics and Molecular Biology
aff
701
citations
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
2020· article· en· Nature Genetics· Medicine
affno abstract
689
citations
Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
2016· article· en· Cancer Cell· Medicine
affno abstract
658
citations
Recombination and the maintenance of plant organelle genome stability
2010· review· en· New Phytologist· Biochemistry, Genetics and Molecular Biology
afffund
567
citations
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
2016· article· en· Nature· Medicine
afffundno abstract
547
citations
Signatures of copy number alterations in human cancer
2022· article· en· Nature· Biochemistry, Genetics and Molecular Biology
aff
516
citations
Targeting Mitosis in Cancer: Emerging Strategies
2015· review· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
496
citations