The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
2012· article· fr· Nature· Medicine
aff
1 630
citations
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Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
2013· article· en· Cancer Cell· Medicine
affsans résumé
842
citations
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
2015· article· en· Nature Medicine· Medicine
affsans résumé
711
citations
Cancer neuroscience: State of the field, emerging directions
2023· review· en· Cell· Medicine
affsans résumé
494
citations
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors
2017· article· en· Science Translational Medicine· Immunology and Microbiology
aff
425
citations
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
2009· article· en· Genes & Development· Biochemistry, Genetics and Molecular Biology
aff
381
citations
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
2011· article· en· Nature· Medicine
fundno affsans résumé
380
citations
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
2016· article· en· The Lancet Oncology· Medicine
afffundsans résumé
369
citations
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia
2016· article· en· Nature Communications· Medicine
aff
296
citations
Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming
2017· article· en· Immunity· Medicine
afffundsans résumé
290
citations
HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC- Driven Medulloblastoma
2016· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
285
citations
BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma
2015· article· en· Journal of Clinical Oncology· Medicine
afffund
285
citations
Enter the Matrix: Factorization Uncovers Knowledge from Omics
2018· review· en· Trends in Genetics· Biochemistry, Genetics and Molecular Biology
afffund
266
citations
ARF GTPases and their GEFs and GAPs: concepts and challenges
2019· article· en· Molecular Biology of the Cell· Biochemistry, Genetics and Molecular Biology
aff
266
citations
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas
2019· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
261
citations
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
2022· article· en· Nature Medicine· Medicine
affsans résumé
255
citations
Standardized annotation of translated open reading frames
2022· letter· en· Nature Biotechnology· Computer Science
afffund
250
citations
Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
2017· article· en· Cancer Cell· Medicine
affsans résumé
228
citations
Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis
2016· article· en· Journal of Clinical Oncology· Medicine
fundno aff
206
citations
Clonal haematopoiesis and risk of chronic liver disease
2023· article· en· Nature· Medicine
affsans résumé
201
citations
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
2020· article· en· Cell· Medicine
afffundsans résumé
198
citations
Glioma Stem Cell–Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
2019· article· en· Cancer Discovery· Biochemistry, Genetics and Molecular Biology
aff
182
citations
Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned
2018· review· en· Trends in Immunology· Immunology and Microbiology
afffundsans résumé
176
citations
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
2020· article· en· Journal for ImmunoTherapy of Cancer· Immunology and Microbiology
fundno aff
175
citations
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment
2019· article· en· Cell Reports· Biochemistry, Genetics and Molecular Biology
aff
170
citations