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Beyond Consent: Respect for Community in Genetic Research

2014· other· en· W1548720582 on OpenAlexaff
Derek J. Jones, Paula Louise Bush, Ann C. Macaulay

Bibliographic record

VenueEncyclopedia of Life Sciences · 2014
Typeother
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsMcGill University
Fundersnot available
KeywordsResearch ethicsCommunity-based participatory researchInformed consentEngineering ethicsParticipatory action researchPolitical scienceSociologyPublic relationsEnvironmental ethicsMedicineEngineering

Abstract

fetched live from OpenAlex

Abstract Paralleling the broadening of scientific thought occasioned by the human genome project, calls have been sounded to expand research ethics to include a principle of ‘respect for community’ in genetic research. The principle is responsive to a history of genetic research that has harmed some groups. The principle recognises that communities hold dignitary interests, values and rights. For such reasons, it has gained recognition in national and international health research ethics norms. To help translate respect for community into research practice, we identify selected ethics elements and research approaches, including: collaborative community research; jointly defining research priorities and questions; informed consent; joint interpretation and dissemination of results; community ethics deliberations and fair benefit sharing. Implementing such elements presents challenges that merit interdisciplinary study, pluralistic debate and analysis. With such work, we project a future with fuller recognition of respect for community as an ethical principle and duty in human research ethics. Key Concepts: Evolving research ethics requires protection of communities, in addition to protection of individuals – this also applies to genetic research. Protection of communities supports the ethical concept of respect for communities. National and international research ethics guidelines support these concepts. Respect for communities can be achieved through researchers using collaborative research with communities. Collaborative research uses principles and practice from both participatory research and community‐engaged research. Collaborative research maximises benefits and minimises harms for communities and groups within the communities. Collaborative research impacts researchers, communities, institutional and community ethics boards and those publishing the results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.030
metaresearch head score (Gemma)0.112
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.130
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0300.112
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.005
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.512
GPT teacher head0.584
Teacher spread0.073 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2014
Admission routes1
Has abstractyes

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