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Assessment of generalizability, applicability and predictability (GAP) for evaluating external validity in studies of universal family‐based prevention of alcohol misuse in young people: systematic methodological review of randomized controlled trials

2012· review· en· W1837422480 on OpenAlex
José Ramón Fernández Hermida, Amador Calafat, Elisardo Becoña, Alexander Tsertsvadze, David Foxcroft

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAddiction · 2012
Typereview
Languageen
FieldMedicine
TopicSubstance Abuse Treatment and Outcomes
Canadian institutionsOttawa HospitalUniversity of Ottawa
FundersPlan Nacional sobre DrogasNational Institutes of HealthUniversity of OxfordNational Institute for Health and Care ResearchOxford Brookes University
KeywordsGeneralizability theoryExternal validityInternal validityRandomized controlled trialPsychologyObservational studySystematic reviewPopulationCriterion validityClinical psychologyPsycINFOMedicineMEDLINEConstruct validityPsychometricsSocial psychologyDevelopmental psychologyEnvironmental health

Abstract

fetched live from OpenAlex

AIMS: To assess external validity characteristics of studies from two Cochrane Systematic Reviews of the effectiveness of universal family-based prevention of alcohol misuse in young people. METHODS: Two reviewers used an a priori developed external validity rating form and independently assessed three external validity dimensions of generalizability, applicability and predictability (GAP) in randomized controlled trials. RESULTS: The majority (69%) of the included 29 studies were rated 'unclear' on the reporting of sufficient information for judging generalizability from sample to study population. Ten studies (35%) were rated 'unclear' on the reporting of sufficient information for judging applicability to other populations and settings. No study provided an assessment of the validity of the trial end-point measures for subsequent mortality, morbidity, quality of life or other economic or social outcomes. Similarly, no study reported on the validity of surrogate measures using established criteria for assessing surrogate end-points. CONCLUSIONS: Studies evaluating the benefits of family-based prevention of alcohol misuse in young people are generally inadequate at reporting information relevant to generalizability of the findings or implications for health or social outcomes. Researchers, study authors, peer reviewers, journal editors and scientific societies should take steps to improve the reporting of information relevant to external validity in prevention trials.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearch
Domain: Reporting · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
gptMetaresearchMeta-epidemiology (broad)
Domain: Reporting · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.083
metaresearch head score (Gemma)0.031
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.330
Threshold uncertainty score0.991

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0830.031
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0240.003
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.535
GPT teacher head0.551
Teacher spread0.015 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it