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Record W1930603020 · doi:10.1371/journal.pone.0133639

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review

2015· review· en· W1930603020 on OpenAlexafffund
Stuart G. Nicholls, Tavis Hayes, Michael McDonald, Charles Weijer, Raphael Saginur, Dean Fergusson

Bibliographic record

VenuePLoS ONE · 2015
Typereview
Languageen
FieldHealth Professions
TopicEthics in medical practice
Canadian institutionsWestern UniversityOttawa Public HealthUniversity of British ColumbiaOttawa HospitalUniversity of Ottawa
FundersCanadian Institutes of Health Research
KeywordsResearch ethicsQuality (philosophy)Engineering ethicsEmpirical researchManagement scienceMedicineData scienceComputer scienceEngineeringEpistemologyPhilosophy

Abstract

fetched live from OpenAlex

BACKGROUND: To date there is no established consensus of assessment criteria for evaluating research ethics review. METHODS: We conducted a scoping review of empirical research assessing ethics review processes in order to identify common elements assessed, research foci, and research gaps to aid in the development of assessment criteria. Electronic searches of Ovid Medline, PsychInfo, and the Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED, were conducted. After de-duplication, 4234 titles and abstracts were reviewed. Altogether 4036 articles were excluded following screening of titles, abstracts and full text. A total of 198 articles included for final data extraction. RESULTS: Few studies originated from outside North America and Europe. No study reported using an underlying theory or framework of quality/effectiveness to guide study design or analyses. We did not identify any studies that had involved a controlled trial--randomised or otherwise--of ethics review procedures or processes. Studies varied substantially with respect to outcomes assessed, although tended to focus on structure and timeliness of ethics review. DISCUSSION: Our findings indicate a lack of consensus on appropriate assessment criteria, exemplified by the varied study outcomes identified, but also a fragmented body of research. To date research has been largely quantitative, with little attention given to stakeholder experiences, and is largely cross sectional. A lack of longitudinal research to date precludes analyses of change or assessment of quality improvement in ethics review.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaMetaresearchResearch integrity
Domain: Evaluation · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewlow
gptMetaresearchResearch integrity
Domain: Methods · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Systematic reviewhigh
models agreeAgreement compares identical category sets and study designs across arms.

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.399
metaresearch head score (Gemma)0.720
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.994
Threshold uncertainty score0.741

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3990.720
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0100.008
Bibliometrics0.0670.055
Science and technology studies0.0050.008
Scholarly communication0.0180.016
Open science0.0050.009
Research integrity0.0060.004
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.960
GPT teacher head0.811
Teacher spread0.149 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

Study designSystematic review
DomainEvaluation · Methods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations82
Published2015
Admission routes2
Has abstractyes

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