Inhibition of Histone Deacetylase Activity by Butyrate
2003· review· en· Journal of Nutrition· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 455
citations
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Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
2006· article· en· Proceedings of the National Academy of Sciences· Neuroscience
aff
772
citations
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
2015· article· en· Nature Medicine· Medicine
affsans résumé
711
citations
Synergistic Induction of Oxidative Injury and Apoptosis in Human Multiple Myeloma Cells by the Proteasome Inhibitor Bortezomib and Histone Deacetylase Inhibitors
2004· article· en· Clinical Cancer Research· Biochemistry, Genetics and Molecular Biology
aff
381
citations
Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat
2005· review· en· Frontiers in Neuroendocrinology· Psychology
affsans résumé
348
citations
Silent Information Regulator 2α, a Longevity Factor and Class III Histone Deacetylase, Is an Essential Endogenous Apoptosis Inhibitor in Cardiac Myocytes
2004· article· en· Circulation Research· Medicine
afffund
302
citations
Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes
2006· article· en· Carcinogenesis· Biochemistry, Genetics and Molecular Biology
aff
256
citations
The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear
2008· article· en· Learning & Memory· Neuroscience
fundno aff
248
citations
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia
2008· article· en· Blood· Biochemistry, Genetics and Molecular Biology
aff
234
citations
Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes
2014· article· en· PLoS Pathogens· Immunology and Microbiology
afffund
206
citations
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
2015· article· en· International Journal of Radiation Oncology*Biology*Physics· Biochemistry, Genetics and Molecular Biology
affsans résumé
203
citations
HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
2005· article· en· Oncogene· Biochemistry, Genetics and Molecular Biology
fundno affsans résumé
176
citations
Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells
2009· article· en· Cell stem cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
169
citations
Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of α-Tubulin Proteostasis in Experimental and Human Atrial Fibrillation
2013· article· en· Circulation· Biochemistry, Genetics and Molecular Biology
afffund
168
citations
Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism
2011· article· en· American Journal Of Pathology· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
157
citations
Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours
2010· article· en· European Journal of Cancer· Biochemistry, Genetics and Molecular Biology
affsans résumé
146
citations
Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin–proteasomal and autophagy systems
2012· article· en· Human Molecular Genetics· Neuroscience
fundno aff
140
citations
Transcription Factor NF-κB Differentially Regulates Death Receptor 5 Expression Involving Histone Deacetylase 1
2005· article· en· Molecular and Cellular Biology· Biochemistry, Genetics and Molecular Biology
afffund
136
citations
Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells
2008· article· en· Journal of Pineal Research· Neuroscience
afffund
135
citations
Vorinostat Induces Reactive Oxygen Species and DNA Damage in Acute Myeloid Leukemia Cells
2011· article· en· PLoS ONE· Biochemistry, Genetics and Molecular Biology
afffund
132
citations
The Histone Deacetylase Inhibitor MS-275 Interacts Synergistically with Fludarabine to Induce Apoptosis in Human Leukemia Cells
2004· article· en· Cancer Research· Biochemistry, Genetics and Molecular Biology
aff
132
citations
Loss of Betaglycan Expression in Ovarian Cancer: Role in Motility and Invasion
2007· article· en· Cancer Research· Biochemistry, Genetics and Molecular Biology
aff
130
citations
Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor
2011· article· en· Kidney International· Biochemistry, Genetics and Molecular Biology
affsans résumé
130
citations
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways
2012· article· en· Cardiovascular Research· Medicine
afffund
129
citations
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy
2010· article· en· Journal of Clinical Investigation· Biochemistry, Genetics and Molecular Biology
afffund
121
citations